Jennifer Thorson, PhD; Research Scientist of Animal Physiology
The over-arching theme of my research is to evaluate nutritional programming of reproductive function in livestock. In particular, the ability of cells in the brain to detect environmental conditions to determine if reproduction is a favorable event. My current work focuses on a population of cells within the arcuate nucleus of the hypothalamus, a nucleus associated with feeding behavior, energy metabolism, and reproductive function. These cells lie in close apposition to leaky vessels from the peripheral circulation as well as the cerebral spinal fluid. As a result of this close apposition, these neurons are at a prime location to monitor the energy state of an animal. Further, this population of cells is implicated in the regulation of the GnRH pulse generator, and thus the subsequent release of gonadotropins and reproductive function. This field of research is therefore relevant in the connection between nutrition and reproductive function and is applicable to animal production and human health.
Bachelor of Science - Equine Science & Agricultural Business - Colorado State University, Fort Collins, CO
Master of Science - Animal Science - North Dakota State University, Fargo, ND
Doctor of Philosophy - Physiology of Reproduction - Texas A&M University, College Station, TX
Postdoctorate - Neuroendocrinology - USDA-ARS-Roman L. Hruska U.S. Meat Animal Research Center, Clay Center, NE
J. F. Thorson, L. D. Prezotto, H. Adams, S. L. Petersen, J. A. Clapper, E. C. Wright, W. T. Oliver, B. A. Freking, A. F. Foote, E. D. Berry, D. J. Nonneman, C. A. Lents. 2018. Energy balance affects pulsatile secretion of luteinizing hormone from the adenohypophesis and expression of neurokinin B in the hypothalamus of ovariectomized gilts. Biology of Reproduction doi ioy069.
D. Prezotto, J. F. Thorson, P. P. Borowicz, J. L. Peine, M. Bedenbaugh, S. M. Hileman, C. A. Lents, J. S. Caton, K. C. Swanson. 2018. Influence of maternal nutrition on visceral metabolism and hypothalamic circuitry of offspring. Domestic Animal Endocrinology 65:71-9.
J. V. Pizol, R. R. Dennis, J. F. Thorson, L. D. Prezotto. 2017. Distribution and clearance of chopped net wrap in the digestive tract of beef cattle. College of Agriculture and Extension Research Report 3:33-5.
C. Korthanke, J. F. Thorson, L. D. Prezotto, T. Welsh, R. Cardoso, G. L. Williams. 2017. Secretion of gonadotropins in response to a novel kiss 1 receptor agonist, RF9 in the mare: Modulation by estradiol-17β and half-life of RF9 in the peripheral circulation. Journal of Equine Veterinary Science 57:100-6.
H. R. Wijesena, C. A. Lents, J. J. Riethoven, M. D. Trenhaile-Grannemann, J. F. Thorson, B. N. Keel, P. S. Miller, M. L. Spangler, S. D. Kachman, D. C. Ciobanu. 2017. Using genomic approaches to uncover sources of variation in age at puberty and reproductive longevity in sows. Journal of Animal Science 95(9):4196-4205.
C. A. Lents, J. F. Thorson, A. T. Desaulniers, B. R. White. 2017. RFamide-related peptide 3 and gonadotropin-releasing hormone-II are autocrine-paracrine regulators of testicular function in the boar. Molecular Reproduction and Development 84(9):994-1003.
J. F. Thorson, N. L. Heidorn, V. Ryu, K. Czaja, D. Nonneman, C. R. Barb, G. J. Hausman, L. D. Prezotto, R. B. McCosh, E. C. Wright, B. R. White, B. A. Freking, W. T. Oliver, S. M. Hileman, C. A. Lents. 2017. Relationship of neuropeptide FF receptors with pubertal maturation of gilts. Biology of Reproduction 96(3):617-34.
J. F. Thorson, A. T. Desaulniers, C. Lee, B. R. White, J. J. Ford, C. A. Lents. 2015. The role of RF amide-related peptide 3 (RFRP3) in regulation of the neuroendocrine reproductive and growth axes of the boar. Animal Reproduction Science 159:60-5.
B. R. C. Alves, R. C. Cardoso, L. D. Prezotto, J. F. Thorson, M. Bedenbaugh, S. M. Sharpton, A. Caraty, D. H. Keisler, L. O. Tedeschi, G. L. Williams, M. Amstalden. 2015. Elevated body weight gain during the juvenile period alters neuropeptide Y-gonadotropin-releasing hormone circuitry in prepubertal heifers. Biology of Reproduction 92(2) 46, 1-10.
R. C. Cardoso, B. R. C. Alves, L. D. Prezotto, J. F. Thorson, L. Tedeschi, D. H. Keisler, M. Amstalden, G. L. Williams. 2014. Reciprocal changes in leptin and NPY during nutritional acceleration of puberty in heifers. Journal of Endocrinology 223(3):289-98.
R. C. Cardoso, B. R. C. Alves, L. D. Prezotto, J. F. Thorson, L. O. Tedeschi, D. H. Keisler, C. S. Park, M. Amstalden, G. L. Williams. 2014. Use of a stair-step compensatory gain nutritional regimen to program the onset of puberty in beef heifers. Journal of Animal Science 92(7):2942-9.
J. F. Thorson, L. D. Prezotto, R. C. Cardoso, S. M. Sharpton,J. F. Edwards, T. H. Welsh, P. K. Riggs, A. Caraty, M. Amstalden, G. L. Williams. 2014. Hypothalamic distribution, adenohyphyseal receptor expression, and ligand functionality of RF-amide-related peptide 3 in the mare during the breeding and non-breeding seasons. Biology of Reproduction 90(2) 28, 1-9.
J. F. Thorson, C. C. Allen, M. Amstalden, G. L. Williams. 2014. Pharmacologic application of native GnRH in the winter anovulatory mare, I: Frequency of reversion to the anovulatory state following ovulation induction and cessation of treatment. Theriogenology 81(4):579-86.
J. F. Thorson, L. D. Prezotto, R. C. Cardoso, C. C. Allen, B. R. C. Alves, M. Amstalden, G. L. Williams. 2014. Pharmacologic application of native GnRH in the winter anovulatory mare, II: Accelerating the timing of pregnancy. Theriogenology 81(4):625-31.
G. L. Williams, J. F. Thorson, L. D. Prezotto, I. C. Velez, R. C. Cardoso, M. Amstalden. 2012. Reproductive seasonality in the mare: neuroendocrine basis and pharmacologic control. Domestic Animal Endocrinology 43(2):103-15.
C. J. Hammer, J. F. Thorson, K. A. Vonnahme, A. M. Meyer, D. A. Redmer, J. S. Luther, T. L. Neville, J. J. Reed, L. P. Reynolds, J. S. Caton. 2011. Effects of maternal plane of nutrition and selenium supply during gestation on passive transfer of immunity and health in neonatal lambs. Journal of Animal Science 89(11):3690-8.
A. M. Meyer, J. J. Reed, T. L. Neville, J. F. Thorson, K. R. Maddock-Carlin, J. B. Taylor, L. P. Reynolds, D. A. Redmer, J. S. Luther, C. J. Hammer, K. A. Vonnahme, J. S. Caton. 2010. Nutritional plane and selenium supply during gestation impact yield and nutrient composition of colostrum and milk in primiparous ewes. Journal of Animal Science 89:1627-39.
W. L. Shelver, J. F. Thorson, C. J. Hammer, D. J. Smith. 2010. Depletion of urinary zilpaterol residues in horses as measured by ELISA and UPLC-MS/MS. Journal of Agricultural and Food Chemistry 58(7):4077-83.
J. F. Thorson, B. J. Karren, M. L. Bauer, C. A. Cavinder, J. A. Coverdale, C. J. Hammer. 2008. Effect of selenium supplementation and dietary energy manipulation on mares and their foals: Foaling data. Journal of Animal Science 88:982-90.
B. J. Karren, J. F. Thorson, C. A. Cavinder, C. J. Hammer, J. A. Coverdale. 2008. Effect of selenium supplementation and dietary energy manipulation on mares and their foals: Selenium concentrations and glutathione peroxidase. Journal of Animal Science 88:991-7.
S. A. Wagner, M. S. Mostrom, C. J. Hammer, J. F. Thorson, D. J. Smith. 2008. Adverse effects of zilpaterol administration in horses: Three cases. Journal of Equine Veterinary Science 28(4):238-43.